Medidata Solutions Schedules Fourth Quarter and Full Year Earnings Conference Call for March 15, 2011

FOR IMMEDIATE RELEASE

Medidata Solutions Schedules Fourth Quarter and Full Year
Earnings Conference Call for March 15, 2011

NEW YORK, N.Y. – March 2, 2011 – Medidata Solutions (NASDAQ: MDSO), a leading global provider of SaaS-based clinical development solutions, today announced that it will release its fourth quarter and full year 2010 financial results before the open of the market on Tuesday, March 15, 2011. Tarek Sherif, chief executive officer, and Bruce Dalziel, chief financial officer, will also hold a conference call at 8:00 a.m. ET for investors and analysts to review these results and discuss the outlook for the first quarter and full year 2011.

To participate by telephone, domestic participants may dial 1-877-303-2528 and international participants may dial 1-847-829-0023. Those interested in participating in the conference call should dial in at least 10 minutes prior to the call to register.

Participants can also join the call via a simultaneous live audio webcast, which will be made available on the “Investor” section of Medidata’s website, http://investor.mdsol.com.

A replay of the conference call can be accessed through Tuesday, March 29, 2011, by dialing 1-800-642-1687 domestically or 1-706-645-9291 internationally, with the passcode 42964639. An archive of the call will also be hosted on the “Investor” section of Medidata’s website, http://investor.mdsol.com, for a limited period of time.

About Medidata Solutions Worldwide
Medidata Solutions (www.mdsol.com) is a leading global provider of SaaS-based clinical development solutions that enhance the efficiency of customers’ clinical trials. For over 10 years, Medidata has consistently brought next-generation innovation to the life science industry to lower the total cost of clinical development through informed trial planning and management, optimized clinical processes and platform interoperability. Medidata’s advanced solutions address key functions throughout the clinical development process including protocol development (Medidata Designer®), trial planning and management (Medidata Grants Manager®, Medidata CRO Contractor®), user and learning management (iMedidata™), randomization and trial supply management (Medidata Balance™), monitoring (Medidata Rave Monitor, Medidata Rave Targeted SDV), Serious Adverse Events capture (Medidata Rave Safety Gateway) and clinical data capture, management and reporting (Medidata Rave®). Our diverse customer base spans biopharmaceutical companies, medical device and diagnostic companies, academic and government institutions, CROs and other research organizations, and includes more than 20 of the top 25 global pharmaceutical companies as well as organizations of all sizes developing life-enhancing medical treatments and diagnostics.

Investor Contact:
Hulus Alpay
Medidata Solutions
212.419.1025
halpay@mdsol.com

Media Contact:
Susan McCarron
Lois Paul & Partners
781.782.5767
Susan_McCarron@lpp.com